The National Institute of Nursing Research (NINR) is commemorating its 30th anniversary by marking past accomplishments and mapping a path for the future. NINR Director Patricia Grady, PhD, RN, FAAN, will describe the Institute’s mission and the implementation of NINR’s strategic plan through four areas of scientific focus: wellness, symptom science, self-management, and end-of-life and palliative care. Looking forward, she will discuss new directions in nursing research opportunities that could guide the future nursing science over the next decade.