Epigenetic mechanisms control gene expression without changing the DNA sequence itself. Recent research progress has shown that epigenetic pathways may provide new therapeutic avenues in cancer. It is now apparent that changes in epigenetic control of gene expression in cancer cells, and surrounding cells in the tumor microenvironment, play a fundamental role in driving tumor development, as well as response to chemotherapy and immune treatment. Come to understand epigenetic effector pathways involved in tumor biology and new approaches to target these pathways in cancer treatment.
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