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Friday, April 29 • 11:15am - 12:15pm
Deletion 17p and BCL-2 Overexpression: Genetic Abnormalities and Their Role in Malignant Cell Survival

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The evasion of apoptosis, a hallmark of cancer, results from an imbalance in the components and complex interactions of the BCL-2 family of proteins.  Anti-apoptotic proteins such as BCL-2 may block cell death in hematologic malignancies including chronic lymphocytic leukemia (CLL).  Additionally, a genetic abnormality, deletion 17p, is associated with poor prognosis in CLL patients.  This symposium discusses the BCL-2 pathway, the clinical significance of deletion 17p, and treatment options in deletion 17p CLL patients.

Sponsored by AbbVie-Genentech

Friday April 29, 2016 11:15am - 12:15pm CDT
Learning Hall Theater 4