Infection in immunocompromised patients often results in increased morbidity and/or mortality, but prevention and protection can be provided through both active and passive immunization. Although most opportunistic infections are not routinely preventable by vaccines, many other community-based infections are avoidable. Do you know if your patients are adequately protected? Do you know the recommended timing of immunizations? Follow patient case studies through diagnosis, treatment, and recovery to see the vital importance of vaccinations for not only for the patient, but also family, friends, and healthcare workers. Get the knowledge you need to help you prevent, protect, and immunize!